Daptomycin for Methicillin-Resistant Staphylococcus aureus Bloodstream Infection and Elevated Vancomycin Minimum Inhibitory Concentrations: Has the Time Come?
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چکیده
منابع مشابه
Daptomycin for methicillin-resistant Staphylococcus aureus bloodstream infection and elevated vancomycin minimum inhibitory concentrations: has the time come?
In this issue, Moore et al [1] provide the first data investigating the results of using an alternative agent in patients with methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infection (BSI) with elevated vancomycin minimum inhibitory concentrations (MICs). In this retrospective analysis, funded by an InvestigatorInitiated Research Grant from Cubist Pharmaceuticals, investigators...
متن کاملEarly high-dose daptomycin for methicillin-resistant Staphylococcus aureus bloodstream infections with elevated vancomycin minimum inhibitory concentrations: ready for prime time?
In this issue of Clinical Infectious Diseases, Murray and colleagues present results from a matched cohort study addressing the clinical conundrum of methicillinresistant Staphylococcus aureus (MRSA) bloodstream infections caused by organisms with elevated vancomycin minimum inhibitory concentrations (MICs) [1]. The investigators conclude that highdose daptomycin treatment led to better outcome...
متن کاملVancomycin Creep and Daptomycin Minimum Inhibitory Concentra- tion in Methicillin-Resistant Staphylococcus aureus
Objective: To determine the in vitro activity of daptomycin and vancomycin against 50 strains of methicillin-resistant Staphylococcus aureus (MRSA) isolated from blood and pus specimens. Material and methods: Fifty consecutive MRSA were isolated from pus (n=25) and blood (n=25) were included in the study. Oxacillin susceptibility was determined by cefoxitin disc diffusion, green colored colonie...
متن کاملOptimizing the detection of methicillin-resistant Staphylococcus aureus with elevated vancomycin minimum inhibitory concentrations within the susceptible range
BACKGROUND Determination of vancomycin minimum inhibitory concentration (MIC) can influence the agent used to treat methicillin-resistant Staphylococcus aureus (MRSA) infection. We studied diagnostic accuracy using E-test and VITEK(®) 2 against a gold standard broth microdilution (BMD) methodology, the correlation between methods, and associations between vancomycin MIC and MRSA phenotype from ...
متن کاملDaptomycin or vancomycin for methicillin-resistant Staphylococcus aureus with a vancomycin minimum inhibitory concentration >1 μg/L.
Correspondence Daptomycin or Vancomycin for Methicillin-Resistant Staphylococcus aureus with a Vancomycin Minimum Inhibitory Concentration .1 mg/L To the Editor—We commend Moore et al for their study comparing the effectiveness and safety of vancomycin and daptomycin in the treatment of bacteremia due to methicillin-resistant Staphylococcus aureus (MRSA) with a vancomycin minimal inhibitory con...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2011
ISSN: 1537-6591,1058-4838
DOI: 10.1093/cid/cir777